11-residue chain
Nerve repair & metabolic recovery
28-day protocol replicating Phase 2 clinical-trial parameters to support nerve regeneration and metabolic repair.
Nerve repair & metabolic recoveryrecommended
The standard 28-day cycle from the clinical-trial parameters.
Route: Subcutaneous: abdominal fat pad or outer thigh.
Timing: First thing in the morning before food, or just before bed if nocturnal nerve pain is the main concern.
Refrigerate (36-46 °F). Use within 3-4 days of mixing. Swirl gently; do not shake.
8-12 weeks off before another cycle.
Why:
What sources report this compound changes, or say to check. A record of the evidence, not targets or advice.
Rose after 28 days of daily ARA 290 in sarcoidosis small fibre neuropathy (blinded placebo-controlled trial); in type 2 diabetes it rose only in those who started more than 1 SD below normal, with no change on placebo.
ARA290: a novel treatment for neuropathic pain in sarcoidosis (blinded placebo-controlled trial)Improved in the ARA 290 group over the 56-day observation (28 days of 4 mg daily plus 28 days off) in a phase 2 trial in type 2 diabetes with painful neuropathy.
Brines 2015, Mol Med: ARA 290 in type 2 diabetes with painful neuropathy (phase 2)Lipid profiles improved in the ARA 290 group over 56 days in the same type 2 diabetes trial; the abstract gives no per-fraction figures (a conference abstract mentions HDL and triglycerides).
Brines 2015, Mol Med: ARA 290 in type 2 diabetes with painful neuropathy (phase 2)