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15-residue chain

BPC-157

Unapproved research peptide popular for tendon, joint and gut recovery; human evidence is a handful of tiny uncontrolled reports

250MCG
Dose
10U
Draw
28D
Cycle

BPC-157 is a synthetic 15-amino-acid peptide sold for recovery. It has no approved use anywhere. The human evidence found is a 16-patient retrospective phone survey of knee injections and a 2-person intravenous safety pilot; everything else is animal work.

PTSEALEDBPC-1575 MGLYOPHILIZED

Protocols

  • Recovery from a tendon or joint injuryrecommended

    Community practice, not from a label or trial: the bottom of the 250-500 mcg/day, 4-12 week range. No trial supports it.

Dosing

  • Community practice, not from a label or trial: 250 to 500 mcg per day, one to two times daily, 3 to 5 times a week, 4 to 12 weeks (Dr Pat Taylor page). The page gives no per-injection amount, and it is a clinic information page, not a trial.
  • Route in the community figure: subcutaneous near the injury site, or oral for the gut (same page).
  • Human reports: the knee-injection survey did not report a dose; the IV pilot gave 10 mg then 20 mg intravenously in 250 mL saline over one hour on two days to two people (PubMed 40131143). Those are not self-dosing figures.

Route & timing

Route: Subcutaneous (community figure, near the injury site). Intra-articular and intravenous use appear only in small clinic reports.

Timing: No reliable figure found in the sources; ask your prescriber or supplier.

Reconstitution

  • Placeholder 5 mg vial plus 2 mL gives 2,500 mcg/mL, so 250 mcg is 10 units on a 100-unit syringe. This is arithmetic, not a sourced instruction.

Reconstitution calculator

Concentration
2500 mcg/mL
Per unit
25 mcg
Draw
10 units
Volume
0.1 mL
Doses per vial
20
Vials for cycle (28 doses), pooled
2
Vials, discard remainder
2
concentration = 5000 / 2 = 2500 mcg/mL
per unit = 2500 / 100 = 25 mcg
units = 250 / 25 = 10
mL = 10 / 100 = 0.1
doses per vial = 5000 / 250 = 20
pooled vials = ceil(250 x 28 / 5000) = 2
discard vials = ceil(28 / floor(20)) = 2

Stability

No reliable figure found in the sources; ask your prescriber or supplier.

Off-cycle

Community cycles are 4 to 12 weeks; no sourced rest period.

Why:

  • The sources give no off-cycle figure and no long-term human safety data.

Stacking rules

  • Never draw into the same syringe as another compound; use separate syringes and distinct injection sites.

Safety

Not an FDA-approved drug. FDA removed it from the 503A Category 2 list on April 15 2026 because the nominators withdrew, which does not make it compoundable; a July 2026 advisory committee recommendation is not yet a rule. Check current status.

Common side effects:

  • Injection-site reactions (10-30%), nausea and headache (1-10%) are listed by one secondary page, which says its own figures do not come from quantified adverse-event data.
  • Long-term human safety is unknown; systematic adverse-event monitoring has not been done.
  • Clinic pages list cancer history, pregnancy and breastfeeding, and anticoagulant use as reasons to avoid it.

Stop and call your prescriber if:

  • Swelling, redness or pain spreading from the injection site
  • Rash, hives or trouble breathing
  • Any new unexplained symptom

Markers to track

No reliable source names a biomarker for this compound.

Sources

BPC-157