Peptide Tracker
← Library

Peptide chain

CJC-1295

Long-acting growth-hormone-releasing hormone (GHRH) analog; unapproved. Two very different forms: no DAC (Mod GRF 1-29) and with DAC

100MCG
Dose
10U
Draw
56D
Cycle

CJC-1295 is a synthetic GHRH analog that is not approved anywhere. The name covers two forms that behave and dose very differently. 'No DAC' (also called Mod GRF 1-29) is short-acting, about 30 minutes half-life per a secondary source, and is injected once to several times a day. 'With DAC' carries a drug-affinity complex and has a half-life of 5.8 to 8.1 days (Teichman 2006), so it is dosed weekly or less. Only the DAC form has published human data; the no-DAC form has none that we found.

PTSEALEDCJC-12952 MGLYOPHILIZED

Protocols

  • Community no-DAC pulse protocolrecommended

    Community practice, not from a label or trial. Applies only to the no-DAC form; do not use it for a DAC vial. The source says 2-3 injections a day; the plan logs one.

Dosing

  • FORM 1, NO DAC (Mod GRF 1-29): Community practice, not from a label or trial: 100 mcg per injection, 2-3 times daily, for 8-12 weeks (Peptide Protocol Wiki research protocol; not from a trial).
  • FORM 2, WITH DAC: trial only, not a use recommendation. Healthy adults got single subcutaneous doses (four ascending levels) or two to three weekly or biweekly doses; 30 and 60 mcg/kg were the best tolerated (Teichman 2006). No community mg-per-week figure was fetched, so none is encoded and no DAC protocol is offered.
  • Do not apply a DAC dose to a no-DAC vial or the reverse: a DAC-sized dose given as a no-DAC schedule would be a large overdose.

Route & timing

Route: Subcutaneous injection (trial: subcutaneous).

Timing: No reliable figure found in the sources; ask your prescriber or supplier.

Reconstitution

  • Bacteriostatic water is the diluent named by the secondary source, with no volume. The water in the protocol is arithmetic for a readable draw (2000 mcg + 2 mL gives 1000 mcg/mL, so 100 mcg = 10 units), not a sourced instruction.

Reconstitution calculator

Concentration
1000 mcg/mL
Per unit
10 mcg
Draw
10 units
Volume
0.1 mL
Doses per vial
20
Vials for cycle (56 doses), pooled
3
Vials, discard remainder
3
concentration = 2000 / 2 = 1000 mcg/mL
per unit = 1000 / 100 = 10 mcg
units = 100 / 10 = 10
mL = 10 / 100 = 0.1
doses per vial = 2000 / 100 = 20
pooled vials = ceil(100 x 56 / 2000) = 3
discard vials = ceil(56 / floor(20)) = 3

Stability

Secondary source: reconstituted no-DAC solution kept at 2-8 C and used within 14-21 days. Not from a label.

Off-cycle

Community: 8-12 week courses, repeatable; no sourced rest period.

Why:

  • The sources give no off-cycle length.

Stacking rules

  • Never draw into the same syringe as another compound; use separate syringes and distinct injection sites.
  • As described by the secondary source: no-DAC CJC-1295 is usually paired with ipamorelin, said to give a larger GH release than either alone (no human trial of the pair was fetched). Use separate syringes even for this pair.

Safety

Not FDA-approved for any use. The DAC form's developer program ended; vials sold online are unapproved research products of unknown purity.

Common side effects:

  • Injection-site reactions (secondary source, no-DAC form).
  • The Teichman abstract says no serious adverse reactions were reported and that the drug was relatively well tolerated, especially at 30 or 60 mcg/kg; specific events are not listed in the abstract.
  • Growth hormone secretagogues raise GH and IGF-1; people with active cancer, pituitary disease or diabetes should only use them under a prescriber.

Stop and call your prescriber if:

  • Swelling of hands or feet, joint pain or numbness in the hands
  • Excessive thirst or urination
  • Any rash, wheeze or swelling of the face

Labs and monitoring:

  • IGF-1 and fasting glucose are the usual checks (inferred from the effect on IGF-I in Teichman 2006; no source lists a schedule).

Markers to track

What sources report this compound changes, or say to check. A record of the evidence, not targets or advice.

Sources

CJC-1295