NAD+

• 6 weeks, 3 shots a week in maintenance

  Upper end of the guide's maintenance range (2-3 times per week).

• 6 weeks, 2 shots a week in maintenancerecommended

  Default: the guide gives 2-3 times per week, and the lower end is the gentler place to start.

• Days 1-3: 25 mg to test tolerance
• Weeks 1-2: 50 mg daily or every other day
• Weeks 3-6: 100 mg, 2-3 times per week

Route: Subcutaneous into a well-cushioned fat pad; outer glute or hip preferred over the abdomen.

Timing: First thing in the morning; evening doses may disrupt sleep.

• 1000 mg vial + 5.0 mL bacteriostatic water = 200 mg/mL (use a 3-5 mL syringe to add the water)
• 25 mg = 12.5 units, 50 mg = 25 units, 100 mg = 50 units
• 10 maintenance doses per vial; 2-3 vials for 6 weeks

Refrigerate (36-46 °F). Use within 28-30 days of first puncture. Do not shake.

6-8 weeks off after a 6-week cycle.

Why:

• Continuous supplementation may suppress the body's own NAMPT salvage pathway.

• Never draw into the same syringe as another compound; use separate syringes and distinct injection sites.
• Keep NAD+ in the glute/hip; ARA-290 and TA1 go in the abdomen.
• Push the plunger over 20-30 seconds to reduce burning.

What sources report this compound changes, or say to check. A record of the evidence, not targets or advice.

• Whole-blood NAD+Reported changeSmall human study

  With oral nicotinamide riboside (a precursor, not injected NAD+) whole-blood NAD+ rose 22%, 51% and 142% at 100, 300 and 1000 mg within 2 weeks, with no significant difference in adverse events vs placebo. No source found for injected NAD+.

  PubMed 31278280: Conze 2019, Sci Rep: NIAGEN (nicotinamide riboside) safety and metabolism, randomized placebo-controlled